Key Takeaways:
- Size Standard: Size 00 is the most widely used capsule size because it balances dose capacity with swallowability, making it the practical default for most DIY supplement routines.
- Machine Matters: The material, design, and cleanability of a capsule filling machine directly affect the quality and safety of every batch you fill, and generic machines frequently cut corners on all three.
- Capsule Integrity: The capsule shell itself is part of your supplement, and choosing single-ingredient, naturally derived options like gelatin or pullulan upholds the same clean standard as the ingredients inside.
Most people searching for a capsule filling machine have no idea what size they actually need. You land on a product page, see a dropdown with sizes like 0, 00, 1, 2, and 3, and suddenly you're Googling what any of that even means. Sound familiar? Picking the wrong size doesn't just waste money; it means capsules that won't close, incorrect dosages, and a frustrating first experience that makes the whole DIY supplement idea feel harder than it should be.
At Blated, we fill capsules. Our machines are designed by people who actually use them, trusted by small businesses, compounding pharmacies, and everyday DIYers alike. We carry one of the largest selections of manual capsule filling machines in the United States, and we have spent years helping people get this right the first time.
Let’s examine why size 00 is the most popular capsule size, what distinguishes a well-built size 00 capsule-filling machine from a generic one, and how to choose the right setup for your volume and goals. We will also walk through what first-time fillers should know before getting started and how to choose the right capsule material for your machine.
Why Size 00 Is the Most Popular Capsule Size
Have you ever noticed that almost every capsule supplement on a pharmacy shelf is roughly the same size? That is not a coincidence. Size 00 has become the industry standard because it hits a sweet spot that most other sizes simply do not: large enough to hold a meaningful dose, small enough that most adults can swallow it without much trouble.
Size 00 capsules are one of the most versatile options available for home fillers and small businesses. Our guide on How to Pick the Best Capsule Size explains how density and dosage interact to determine the right fit. Whether you are working with greens, BCAAs, mushroom powders, or any other supplement, a 00 capsule can typically accommodate a solid single-serving dose in just one or two capsules. The exact amount depends on the density of your specific powder, which varies by ingredient. Blated's capsule size chart and calculator at blated.com are the most reliable way to know what your powder will actually yield per capsule.
That capacity and versatility are exactly why demand for the capsule filling machine 00 consistently outpaces every other size in searches, sales, and community discussions. For most people starting out with DIY supplementation, size 00 is the practical default, and for many, it stays that way long after they have tried other sizes.
What To Look For In A Size 00 Capsule Filling Machine
Not all capsule filling machines are built the same, and the differences matter more than most product listings let on. A cheaper capsule filler 00 might look identical to a well-built one in photos, but the materials, design, and serviceability tell a completely different story once you use it. Here are three things worth paying close attention to before buying:
Material Safety And Color Contact Points
Most people never think to ask what color the parts of their capsule filler are, but it is actually worth considering. Machines with black or heavily dyed components can expose your powder to synthetic dyes and fillers during the filling process. Blated's Core Series machines are manufactured so that only clear and white components come into contact with your ingredients.
Build Quality And Cleanability
A capsule filler that cannot be cleaned properly is one you cannot trust. Residue buildup between batches is a real concern, especially for people switching between different supplements. Blated's Pro Series machines feature tool-free disassembly via hand-removable bolts, making deep cleaning, part replacement, and adjustment faster and more thorough than anything a fixed, non-disassembling design allows.
Instructions And Ongoing Support
A machine is only as useful as your ability to operate it correctly. Many generic capsule fillers ship with instructions that skip critical steps, leaving users to troubleshoot on their own. Blated provides the most complete practical guidance available, backed by real human customer support that actually knows the product.
Blated's Size 00 Capsule Fillers: Core Series vs. Pro Series
Blated offers several size-00 capsule-filling machine models, each built for a different output level. Understanding what separates them helps you avoid buying more machines than you need, or worse, not enough. Here is a breakdown of what each model brings to the table:
Choosing the Right Size 00 Capsule Machine: Core Series 100-Hole
The 100-hole model is the most approachable starting point for someone new to DIY supplementation. It is a reasonable fit for personal use and small batches, and its compact size means it takes up minimal counter space, which matters if you are working in a home kitchen or small prep area.
Core Series 400-Hole
The 400-hole model is a natural step up for anyone who has outgrown single trays or wants to fill larger batches in one session. At around 20 minutes per tray, it significantly reduces the time spent per capsule compared to the 100-hole tray. It is a popular choice among small businesses and serious home users who supplement their daily intake.
Pro Series 800-Hole
The 800-hole Pro Series is built for high-output filling, completing a full tray in approximately 30 minutes. It is worth noting that this model is larger and heavier than the 100- and 400-hole options, with all parts weighing around 25 pounds, so a dedicated setup space should be planned for.
High-Volume Filling: When To Consider The Pro-Op 300
There is a point in every serious filler's routine where manual filling starts to feel like the bottleneck. You are no longer a hobbyist; your batches are growing, and spending 20 to 30 minutes per tray is time you could be spending elsewhere. Many of Blated's longtime customers started with a capsule filler size 00 manual model and moved to the Pro-Op 300 as their volume grew, and the reasons why become clear pretty quickly:
Time Savings That Actually Add Up
The Pro-Op 300 fills 300 capsules in roughly 5 to 6 minutes, which is a meaningful difference compared to any manual model in the lineup. For someone filling multiple batches per week, that gap compounds quickly. What took an hour can realistically be done in under 15 minutes with the right setup.
Built For Consistent, Repeatable Output
High-volume filling demands reliability as much as speed. The Pro-Op 300 is designed to deliver consistent fills across every tray, which becomes increasingly important as you produce capsules for others, whether for a small business, a clinic, or a community group. Predictable output at that scale is not a bonus; it is a requirement.
A Natural Upgrade Path
Starting with a 100-hole manual model and graduating to the Pro-Op 300 is a path many of Blated's longtime customers have naturally taken. As batch sizes grow, the gap between what a manual machine can comfortably handle and what the Pro-Op 300 delivers becomes hard to ignore. It is less of an upgrade and more of a logical next step for anyone whose volume has outgrown the manual process.
Loading Your Capsules: What First-Timers Should Know
Manual capsule filling has a learning curve, and most of the frustration people run into comes from skipping over a few details that are easy to miss the first time. Our How to Use Your Capsule Filler Core Series guide walks through every step in full detail. Knowing what to expect before you start makes the whole process go smoother from the very first batch. Here is what is worth understanding going in:
Both Halves Load Separately
On every manual capsule filling machine, the larger capsule half and the smaller cap are loaded into the tray separately. This is not a design flaw; it is simply how two-piece capsules work. The good news is that Blated offers pre-separated capsules that skip the manual separation step entirely, saving meaningful time, especially when you are filling larger trays.
The Quick Flip Trick
For anyone using standard, unseparated capsules, the Quick Flip Trick is a technique Blated teaches that significantly speeds up the separation process. Instead of pulling each capsule apart by hand, the method uses the tray itself to do most of the work. It is one of those small adjustments that makes a noticeable difference once you have seen it done.
Finding Your Powder Density First
Knowing your powder's density before filling helps you predict how much each capsule will hold, which takes the guesswork out of dosing. You do not have to pre-weigh every batch before loading a tray; plenty of people fill first and weigh after to determine dosage. Blated's Capsule Size Calculator is the most practical starting point for getting familiar with your specific powder.
Choosing The Right Empty Size 00 Capsules For Your Machine
The capsule-filling machine gets most of the attention, but the capsules you fill it with matter just as much. A well-built machine paired with low-quality or poorly labeled capsules undermines the whole point of making your own supplements in the first place. Here is what to consider when choosing your size 00 capsules:
Gelatin Capsules
Gelatin capsules are the most widely used option and the standard choice for most home fillers. They are derived from animal sources, clean up well, and work reliably across a wide range of powder types. Blated carries single-ingredient gelatin capsules with no added fillers, binders, or preservatives, which is more than can be said for many capsules sold elsewhere.
Pullulan Capsules For A Natural Vegan Option
Pullulan is a naturally occurring material derived from fermented tapioca starch, making it a genuinely plant-based alternative to gelatin. For anyone following a vegan or vegetarian lifestyle, pullulan is the material Blated recommends without reservation. It performs comparably to gelatin in most filling applications and meets a standard that synthetic alternatives simply do not.
Why Blated Does Not Recommend HPMC
HPMC, or hydroxypropyl methylcellulose, is commonly marketed as a vegan capsule material, but it is an artificially modified cellulose material, not a naturally occurring one. Blated does not consider it a true vegan option and finds the way it is typically labeled misleading to consumers. When ingredient integrity is the whole reason you are making your own supplements, the capsule shell itself should meet the same standard as everything you put inside it.
Final Thoughts
Size 00 is the right starting point for most people, and the machine you pair it with determines how clean and consistent every batch will be. If you are still working out how much your powder will fill, start with Blated's capsule size chart and calculator at blated.com. To compare machines side by side, the Core vs. Pro Series Capsule Fillers comparison page is the most direct next step.
Frequently Asked Questions About Capsule Filling Machine 00
Can I use a size 00 capsule filling machine for liquids or oils?
Manual capsule filling machines are designed for powdered ingredients. Filling capsules with liquids or oils requires a different type of capsule and a separate process altogether. For powdered supplements, a standard 00 capsule filler works well across a wide range of ingredients.
How many capsules do I need to fill a full batch?
A full tray depends on the model you are using. The 100-hole model fills 100 capsules per batch; the 400-hole model, 400; and so on. Stocking up on a larger supply of capsules beforehand means fewer interruptions between batches, especially if you are filling regularly.
Do size 00 capsules work with all capsule filling machines?
Not all machines are sized the same way, so it is important to confirm that the machine you purchase is specifically designed for size 00 capsules. Blated's size 00 machines are built and tested for that size, so compatibility is not something you need to second-guess when buying from their lineup.
What is the difference between a capsule filler 00 and a pill press?
A pill press, also called a tablet press, compresses powder into a solid tablet using binders and pressure. A capsule filler is a separate device that fills two-piece shell capsules with powder. Most home users searching for a pill filler or pill press are actually looking for a capsule filler, since capsules require no binders or compression equipment.
How do I know if my powder is too coarse or too fine for size 00 capsules?
Powder texture can affect how well a capsule fills and closes. Very coarse powders may not pack evenly, while extremely fine powders can create air pockets. Running a small test batch before committing to a large fill session is a practical way to identify issues early.
Can a 00 capsule filling machine be used for pet supplements?
Blated's capsule-filling machines are trusted by veterinarians, making them a legitimate option for preparing powdered animal supplements. That said, any decision to supplement your pet's diet should involve a veterinarian familiar with your pet's specific needs.
How should I store filled size 00 capsules after a batch?
Filled capsules should be stored in a cool, dry place, away from direct light and humidity. Moisture is the main concern, as it can cause capsule shells to soften or stick together over time. Airtight containers work well for maintaining capsule integrity between uses.


